|Pollard Group -- Gladstone Institutes, UC San Francisco|
We develop and apply
statistical methods for
the comparative analysis
of genomic data.
Current projects include
detecting fast evolving
regions of the primate
genome and studying
using metagenomic data.
November 2013: Using a combination of
bioinformatics and experimental approaches, we showed that many
Human Accelerated Regions (HARs) function as developmental
enhancers, some with differences in activity between humans and
chimps. The paper
was published in a special theme issue of Phil Trans Royal Society B
on enhancer evolution. Images of HAR enhancers can be viewed through
our EnhancerBrowser website. More info here.
November 2013: Postdoc Josh Ladau and Katie Pollard used niche modeling to predict microbial community diversity in the tallgrass prarie of the United States before agriculture dramatically changed this ecosystem. This project was a collaboration with Noah Fierer and others at University of Colorado. The paper was published in Science and appeared in Nature News. More info here.
October 2013: Katie Pollard and Gladstone President Sandy Williams were confirmed as Fellows of the California Academy of Sciences (news story here).
September 2013: Katie participated in The New Diagnosis, a panel discussion of technology in health care and research at TechCrunch Disprut 2013.
September 2013: The Pollard lab's work on the human gut microbiome was featured on ABC News. We are collaborating with Shomi Sanjabi's lab to study changes in the gut microbiome during the onset of autoimmune disease.
August 2013: Katie Pollard was featured in an Amstat News story about the benefits of postdoctoral fellowships. Amstat News is the magazine of the American Statistical Association.
May 2013: The Pollard lab's investigations into the human microbiome and its role in autoimmune diseases was covered in a news story on KQED radio. The lab is collaborating with Carlos Bustamante and colleagues to study the microbiomes of Khoisan people in South Africa (more info here).
October 2012: Our collaborative work with Benoit Bruneau's lab on the epigenetics of heart development was published in Cell and featured on ABC News.
July 2012: The Gordon and Betty Moore Foundation awarded the Pollard lab $1.3 million for research into the global mapping of microbial functions using metagenomic data. This project is a collaboration with the laboratory of Jonathan Eisen at UC Davis that builds upon our iSEEM Project.
June 2012: The Pollard lab and colleagues published the initial results of the Human Microbiome Project in Nature and PLoS ONE. We analyzed microbial community DNA from 18 body sites of 242 healthy adults living in St. Louis and Houston. The Pollard lab's main contribution was establishment of a rigorous procedure for identifying novel types of microbes, which we used to characterize new gut bacteria, including several members of the recently discovered genus Barnesiella. Our work was featured on ABC News and was selected as the NHGRI Genomic Advance of the Month. (Press Release)
June 2012: Several of our discoveries about Human Accelerated Regions were featured in a story about human evolution in the New Scientist.
September 2011: Postdoc Samantha Riesenfeld was awarded an NRSA Fellowship from the National Institute of Child Health and Human Development to study vertebrate gene regulatory elements in collaboration with Nadav Ahituv.
August 2011: The Pollard lab received a 4-year $1.5 million grant from the National Science Foundation's Mathematical Biology Program to explore the human microbiome through development of novel convex geometry and comparative genomics approaches.
January 2011: Postdocs Tony Capra and Samantha Riesenfeld were both awarded Informatics Fellowships from the PhRMA Foundation.
June 2010: Katie Pollard appeared on Episode 2 of The Age of the Genome, a BBC Radio special hosted by Richard Dawkins. The lab was also featured on the UCSF Science Cafe.
April 2010: Our approach to studying human-chimp differences in non-coding DNA was featured in Ursula Goodenough's NPR Blog.
January 2010: The Pollard Lab and Gladstone Bioinformatics Core were awarded NHLBI funds to study the epigenetics of heart development in a collaborative project with Benoit Bruneau and others. The Gladstone team is part of a nation-wide consortium called Bench to Bassinet.
December 2009: Katie Pollard was featured in a John Rubin documentary entitled What Darwin Never Knew, that aired December 29 on NOVA. She is featured in an accompanying on-line interivew about The DNA of Human Evolution.
October 2009: The Gladstone Institutes Science for Life lecture featured Katie Pollard talking about human evolution and Erin Wang playing cello pieces from different periods in the evolution of the instrument.
October 2009: Katie Pollard appeared on the German science TV program Quarks & Co.
July 2009: Katie Pollard and Nadav Ahituv received a UCSF Program for Breakthrough Biomedical Research (PBBR) Integrative Research Award. The one-year grant supports collaborative, interdisciplinary research on a high-risk topic.
June 2009: Katie Pollard appeared on Are We Alone?, a SETI Radio program that aired on Public Radio station KALW.
May 2009: Our research about human-chimp genetic differences was featured in the National Institutue of General Medical Sciences (NIGMS) Magazine Computing Life and the NIH Biomedical Beat news digest.
Katie Pollard's article entitled What Makes Us Human? was the Scientific American cover story in May 2009. Our comparative genomics research was featured on ABC News (click on second photo to play video).